Biological and hematological changes in experimental cryptosporidiosis

In experimentally infected laboratory-bred white rats, Cryptosporidium infection rate was higher among immunosuppressed [75%] than immunocompetent ones [37.5%] with statistically insignificant difference. Cryptosporidiosis was found to be a fatal disease especially in immunosuppressed rats [50%]. There was also marked flourishing of the infection as revealed by high intensity of infection in immunosuppressed than the immunocompetent rats [363 and 82.7 oocysts / pellet respectively]. In spite of the severe disease, cyclophosphamide appeared to have no effect on the prepatent period. In both immunosuppressed and immunocompetent infected rats, there was a decrease in the total leucocytic count with marked lymphocytopaenia. This indicates decreased resistance to infection, thus higher oocyst counts in the pellets

specificity of leishmaniasis IHAT in albino rats experimentally infected with toxoplasma gondii and hymenolepis nana

The specificity and sensitivity of the indirect haemagglutination test [I.H.A.T.] in the diagnosis of human leishmaniasis have been previously reported. As far as rodent reservoirs are concerned, no data are available about its specificity. In the present paper, it was aimed to study the specificity of this test against two of the common parasites of man and rodents in Egypt, T. gondii and H. nana. It was concluded that the leishmaniasis I.H.A. reactions at dilution up to 1:32 are not specific when dealing with rodents' sera

Critical assessment of eosinophilia versus some immunologic tests in human hydatidosis in Egypt

A marked disconcordance was observed between eosinophilia on one side and Casoni test, C.F.T., T.H.A.T. and A/G ratio on the other side in 350 cases. This was attributed to the fact that eosinophilia occurs in a wide range of parasitic diseases and allergic conditions prevailing in Egypt. The results showed that A/G ratio was not sensitive, the marked discrepancy between the I.H.A.T. and C.F.T. and that Casoni test is not highly specific. The value of eosinophilia as an indirect evidence of infection should not be overlooked

Serological demonstration of toxoplasmosis among sheep in Sudan

Numerous reports from all over the world attest the widespread prevalence of toxoplasmosis in man and animals. Despite this fact, the disease has not been so far studied in Sudan. This paper is intended to report on the presence of antibodies against T. gondii among sheep as indicated by the Sabin and Feldman dye test and complement fixation test. The results were discussed on the light of work done in other countries

specificity of leishmaniasis indirect hemagglutination in dogs experimentally infected with toxoplasma gondii and eschinoccus granulosus

Indirect haemagglutination test proved to be sensitive and specific for the diagnosis of human leishmaniasis. As far as dogs are concerned, no data are available about its specificity. In the present study, the specificity was tested against two common parasites of dogs, T. gondii and E. granulosus. The results showed that leishmaniasis I.H A. reaction at dilution 1: 16 is not specific. It may be a cross reaction with echinococcosis or toxoplasmosis

Specificity and sensitivity of indirect hemagglutination in patients with cutaneous leishmaniasis

The specificity and sensitivity of leishmaniasis I.H.A. test in 27 patients with active cutaneous leishmaniasis and ten patients with active schistosomiasis mansoni were studied. It was found that the test has little value for the diagnosis of cutaneous leishmaniasis and no real cross reaction occurs with schistosomiasis

Leishmaniasis in rodents caught in Suez Canal zone, Egypt

Wild rodents were trapped alive in Port Said Governorate and Ismailia Governorate [Suez Canal Zone]. Blood samples were taken directly from the heart by disposable syringes. Sera were separated and examined for antibodies. The work is based on Leishmaniasis indirect haemagglutination tests, examination of blood films taken from the tail and careful inspection for any cutaneous induration or sore. Sero-positive reaction with titers up to 1:64 in Rattus rattus alexandrinus and 1:512 in R. norvegicus were detected. Both cutaneous inspection and blood films examination gave negative findings. The history of Leishmaniasis in Egypt is reviewed and the significance of Leishmania infection in rodents is discussed